This alignment was made using the MULTALIN server at the PBIL in Lyon, France. The default settings for sequence comparison were accepted without revision.
10 20 30 40 50 60| | | | | |aTTP_32kDa ------------------------------------------MAEARSQPSAGPQLNALPCRALBP_human MSEGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETRETAP_45kDa -------------------------------------------------------MSGRVPTPASE_MEG2 ---------------------------------------------MEPATAP---RPDMASec14p -------------------------------------QQEKEFLESYPQNCPPDALPGTPConsensusPrim.cons. MSEGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPC2Q22233E44PQ44P333LPGRP70 80 90 100 110 120| | | | | |aTTP_32kDa DHSPLLQPGLAALRRRAREAGVPLAPL--PLTDSFLLRFLRARDFDLDLAWRLLKNYYKWCRALBP_human EAVRELQEMVQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNFTAP_45kDa GDLSPRQKEALAKFRENVQD-V-LPALPNPDDYFL-LRWLRARSFDLQKSEAMLRKHVEFPTPASE_MEG2 PELTPEEEQATKQFLEEINKWT-VQYNVSPLSWNVAVKFLMARKFDVLRAIELFHSYRETSec14p GNLDSAQEKALAELRKLLED----AGFIERLDDSTLLRFLRARKFDVQLAKEMFENCEKWConsensus l #e a a r # v a pld lrflrARkF#v a e$l yPrim.cons. G5L5PLQE5ALAQFRE55ED3V22A5LV4PLDDSFLLRFLRARKFDVQ2A5ELLRNYV22130 140 150 160 170 180| | | | | |aTTP_32kDa RAEC-------------PEISADLHPRSIIGLLKAGYHGVLRSRDPTGSKVLIYRIAHWDCRALBP_human RLQY-------------PELFDSLSPEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQTAP_45kDa RKQKDIDNIIS---WQPPEVIQQYLSGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDPTPASE_MEG2 RRKEGIVKLKP---HEEP-LRSEILSGKF---------TILNVRDPTGASIALFTARLHHSec14p RKDYGTDTILQDFHYDEKPLIAKFYPQYYHKTDKDGRPVYFEELGAVNLHEMNKVTSEERConsensus R pel p g p l rdp g lfPrim.cons. RKQYGID3I33DFH33EPELIA5LLPG554GTDK2GYP2VL5SRDPTGAKV2LF52S5WD190 200 210 220 230 240| | | | | |aTTP_32kDa PKVFTAYDVFRVSLITSELIVQEVETQRNGIKAIFDLEGWQFSHAFQITPSVAKKIAAVLCRALBP_human SQEITFDEILQAYCFILEKLLENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLTAP_45kDa LLRTKMREC-ELLLQECAHQTTKLGRKVETITIIYDCEGLGLKHLWKPAVEAYGEFLCMFPTPASE_MEG2 PHKSVQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYANF---ELDLGKKVLNLLSec14p MLKNLVWEYESVVQYRLPACSRAAGHLVETSCTIMDLKGISISSAYS-VMSYVREASYISConsensus e l etq #g I # G a s k lPrim.cons. PLK5T55EVLQ2LLY5LE55V555ETQ2NGICIIYDL2G555SHA4S355S552K5L5ML250 260 270 280 290 300| | | | | |aTTP_32kDa TDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKERIHMHGNNYKQSLLQHFP-DILPCRALBP_human QDSFPARFKAIHFIHQPWYFTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDE-NILPTAP_45kDa EENYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVPPTPASE_MEG2 KGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTS---EVTQHLPRECLPSec14p QNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFILGSSYQKELLKQIPAENLPConsensus %P r k ! aP F % ikpfL k er! lg ll h p # lPPrim.cons. QDSFP2RLKKIHIINAP55F52AY2LIKPFLKEKTRERIF2LG52YK4ELL2HIP32ILP310 320 330 340 350 360| | | | | |aTTP_32kDa LEYGG--EEFSMEDICQEWTNFIMKSEDYLSSISESIQ----------------------CRALBP_human SDFGG--TLPKYDGKAVAEQLFGPQAQAENTAF---------------------------TAP_45kDa VEYGGTMTDP--DGNPKCKSKINYGGDIPRKYYVRDQVKQQYEHSVQISRGSSHQVEYEIPTPASE_MEG2 ENLGGYVKIDLATWNFQFLPQVNGHPDPFDEIILFSLPPALDWDSVHVPGPHAMTIQELVSec14p VKFGGKSEVDESKGGL-YLSDIGPWRDPKYIGPEGEAPE---------------------Consensus GG g #Prim.cons. VE2GG3325244DGN5Q5LS522P55DP5555I44S4P322222SV22222222222222370 380 390 400 410 420| | | | | |aTTP_32kDa ------------------------------------------------------------CRALBP_human ------------------------------------------------------------TAP_45kDa LFPGCVLRWQFMSDGADVG----FGIFLKTKMGERQRAGEMTEVLPNQRYNSHLVPEDG-PTPASE_MEG2 DYVNARQKQGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHSec14p ------------------------------------------------------------ConsensusPrim.cons. 2222222222222222D22RENP2G2F2222222222222222V222222222L2222GH430 440 450 460 470 480| | | | | |aTTP_32kDa ------------------------------------------------------------CRALBP_human ------------------------------------------------------------TAP_45kDa TLTCSDPGIYVLRFDNTYSFIHAKKVNFTVEVLLPDKASEEKMKQLGAGTPK--------PTPASE_MEG2 TQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCSec14p ------------------------------------------------------------ConsensusPrim.cons. T2T22222222222222222I222222222222222222E2K2222222T22EEGGRRKC490 500 510 520 530 540| | | | | |aTTP_32kDa ------------------------------------------------------------CRALBP_human ------------------------------------------------------------TAP_45kDa ------------------------------------------------------------PTPASE_MEG2 GQYWPLEKDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGSec14p ------------------------------------------------------------ConsensusPrim.cons. GQYWPLEKDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYG550 560 570 580 590 600| | | | | |aTTP_32kDa ------------------------------------------------------------CRALBP_human ------------------------------------------------------------TAP_45kDa ------------------------------------------------------------PTPASE_MEG2 VPSSAASLIDFLRVVRNQQSLAVSNMGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLSec14p ------------------------------------------------------------ConsensusPrim.cons. VPSSAASLIDFLRVVRNQQSLAVSNMGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICL610 620 630 640 650 660| | | | | |aTTP_32kDa ------------------------------------------------------------CRALBP_human ------------------------------------------------------------TAP_45kDa ------------------------------------------------------------PTPASE_MEG2 AQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEKEGMVSSGQNLLAVESSec14p ------------------------------------------------------------ConsensusPrim.cons. AQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEKEGMVSSGQNLLAVESaTTP_32kDa -CRALBP_human -TAP_45kDa -PTPASE_MEG2 QSec14p -ConsensusPrim.cons. Q