Home

People in the Department

Contacts

Research

Student Information

Course Materials

Odds & Ends

Department of Chemistry - Brock University
Contact Research Publications Research Group Courses Useful Links

Jeffrey K. Atkinson: Publications

Scott W. Leonard, Elaine Paterson, Jeffrey Atkinson, Rajasekhar Ramakrishnan, Carroll E. Cross, & Maret G. Traber. Studies in humans using deuterium-labeled alpha– and gamma–tocopherols demonstrate faster plasma gamma–tocopherol disappearance and greater metabolite production. Journal of Nutrition 2004 (In press)

Lawson KA, Anderson K, Simmons-Menchaca M, Atkinson J, Sun L, Sanders BG, Kline K.
Comparison of vitamin E derivatives alpha-TEA and VES in reduction of mouse mammary tumor burden and metastasis.
Exp Biol Med. 2004, 229(9), 954-63.

Samantha Morley, Candance Panagabko, Diana Shineman, Achim Stocker, Jeffrey Atkinson and Danny Manor Molecular Determinants of Heritable Vitamin E Deficiency. Biochemistry 2004, 43, 4143-4149.

Ming-Chieh Shun, Weiping Yu, Jeffrey Atkinson, Abdul Gapor, Bob G. Sanders, and Kimberly Kline Pro-apoptotic Mechanisms of Action of a Novel Vitamin E Analog (alpha-TEA) and a Naturally Occurring Form of Vitamin E (delta-Tocotrienol) in MDA-MB-435 Human Breast Cancer Cells. Nutrition and Cancer 2004, 48(1), 95-105

Scott W. Leonard, Richard S Bruno, Elaine Paterson, Bettina Schock, Jeffrey Atkinson, Tammy M. Bray, Carroll E Cross, and Maret G. Traber. 5-Nitro-gamma-tocopherol increases in human plasma exposed to cigarette smoke in-vitro and in-vivo. Free Radicals in Biology and Medicine 2003, 35(12):1560-7

Galli F, Lee R, Atkinson J, Floridi A, Kelly FJ. Gamma-Tocopherol biokinetics and transformation in humans. Free Radic Res. 2003, 37(11):1225-33.

Bradford A, Atkinson J, Fuller N, Rand RP. The effect of vitamin E on the structure of membrane lipid assemblies. J Lipid Res. 2003, 44(10):1940-5.

Lawson KA, Anderson K, Menchaca M, Atkinson J, Sun LZ, Knight V, Gilbert B, Conti C, Sanders BS, Kline K. Novel Vitamin E Analog Inhibits Syngeneic Mouse Mammary Tumor Growth and Blocks Lung Metastasis. Molecular Cancer Therapeutics. 2003 Molecular Cancer Therapeutics. 2003, 2, 437-444

Candace Panagabko, Samantha Morley, Marta Hernandez, Patrick Cassolato, Heather Gordon, Rachel Parsons, Danny Manor and Jeffrey Atkinson.   Ligand specificity in the CRAL-TRIO protein family. Biochemistry  2003, 42(21), 6467-6474

Solomon Fixon-Owoo,  Frédéric Levasseur,  Keith Williams, Thomas N. Sabado, Mike Lowe, Markus Klose, A. Joffre Mercier, Paul Fields, Jeffrey Atkinson.  Preparation and Biological Assessment of Hydroxycinnamic Acid Amides of Polyamines In press: Phytochemistry 2003, 63(3):315-34.

Panagabko, C., Neely, S., Lei, H., Morley, S., Manor, D., and Atkinson, J. Expression and refolding of recombinant human alpha-tocopherol transfer protein (alpha-TTP) capable of specific alpha-tocopherol binding.  Protein Expression and Purification. 2002, 24, 395-403

Klose, M.K., Atkinson, J.K., and Mercier, A.J.  Effects of a hydroxycinnamoyl conjugate of spermidine on arthropod neuromuscular junctions. J Comp Physiol A, 187:945-952, 2002

Galli, F., Lee, R., Dunster, C., Atkinson, J.K., Floridi, A.,  and Kelly, F.J.  Gamma-tocopherol metabolism and its relationship with alpha-tocopherol in humans: a stable isotope supplementation study. Biofactors 2001 15(2-4), 65-69

Lei, Huangshu; Jeffrey Atkinson. Hydrogen-deuterium scrambling during the reductive deuteration of alpha- and gamma-tocopherol chromenes Journal of Labeled Compounds and Radiopharmaceutical. 2001, 44, 215-223.

Lei, Huangshu,; Atkinson, J.K. Synthesis of phytyl and chroman derivatized photoaffinity labels based on a-tocopherol. Journal of Organic Chemistry. 2000, 65(8); 2560-2567.

Panagabko, C.; Chenier, D.; Fixon-Owoo, S.; Atkinson, J.K. Ion-pair HPLC determination of hydroxycinnamic acid monoconjugates of putrescine, spermidine and spermine. Phytochemical Analysis , 2000, 11, 11-17.

Lei, H.; Marks, V.; Pasquale, T.; Atkinson, J.K. Synthesis of photoaffinity label analogues of a-tocopherol. Bioorg. Med. Chem. Letters, 1998 8, 3453-3458.

Mercier, A. Joffre; Farragher, Suzanne; Schmor, B.; Kamau, M.; Atkinson, J. Effect of a plant derived spider-toxin analogue on the crayfish neuromuscular junctions. Canadian Journal of Zoology, 1998, 76, 2103-2107.

Tays, K.; Atkinson, J.K. An improved synthesis of cyclic hydroxamic acids from Gramineae. Synthetic Communications, 1998 28(5), 903-912.

Sen, A.; Bergvinson, D.; Miller, S; Atkinson,J.K.; Fulcher, G.; Arnanson, J.T. Distribution and microchemical detection of phenolic acids, flavanoids and phenolic acid amides in maize kernels. J. Chem. Ecol. 1994 42, 1879-1883

Palli, S. R.; Touhara, K; Charles, J.-P.; Bonning, B.C.; Atkinson, J.K.; Trowell, S. C.; Hiruma, K.; Goodman, W.G.; Kyriakides, T; Prestwich, G.D.; Hammock, B. D. and Riddiford, L.M. A nuclear juvenile hormone binding protein from larvae of Manduca sexta: A putative receptor for the metamorphic action of juvenile hormone. Proceedings of the National Academy of Science USA, 1994, 91, 6191-6195.

J.K. Atkinson, J. Arnason, F. Campos, H.M. Niemeyer, H.R. Bravo, "Synthesis and Reactivity of Cyclic Hydroxamic Acids: Resistance Factors in the Gramineae", Chapter 32 in Synthesis and Chemistry of Agrochemicals, Vol. III, ed. by D.R. Baker, J.G. Fenyes and J.J. Steffens, ACS Symposium Series, 504, 349-360 (1992).

J. Atkinson, P. Morand, J.T Arnason, H.M. Niemeyer, H. Bravo, "Synthesis of Analogues of the Cyclic Hydroxamic Acid 2,4-Dihydroxy- 7-Methoxy-1,4-Benzoxazin-3-One (DIMBOA): Their pH Dependent Decomposition and Reaction with Mercaptoethanol", J. Org. Chem., 56, 1788-1800 (1991).